Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.39 |
| ▸ | CD38 | P28907 | 3/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | GRK6 | P43250 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29757105 | 0.84 | RIPK1 (0.49) | ARRIPK1MPO | |
| SCHEMBL24193617 | 0.82 | RIPK1 (0.45) | ARRIPK1CD38KLKB1CYP3A4 | |
| SCHEMBL29757046 | 0.79 | HCAR2 (0.50) | RIPK1MPOKLKB1PARP1CDC7 | |
| SCHEMBL24193842 | 0.78 | ALPL (0.48) | RIPK1KLKB1ALPL | |
| SCHEMBL23085471 | 0.77 | NR1H2 (0.53) | RIPK1KLKB1ALPL | |
| SCHEMBL29757084 | 0.76 | RIPK1 (0.44) | RIPK1MPOALPLMAPK8 | |
| SCHEMBL15964866 | 0.73 | CA5A (0.43) | ARCA5ACD38MPOMAPK8 | |
| SCHEMBL9734415 | 0.72 | LMNA (0.44) | ARCD38MPOCYP3A4 | |
| SCHEMBL30035399 | 0.72 | AR (0.46) | ARRIPK1CD38PARP1CYP3A4 | |
| SCHEMBL25760819 | 0.72 | ALPL (0.43) | RIPK1KLKB1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098922-A | Anticonvulsants | CIBA-GEIGY CORPORATION (US) | 1992-03-24 | — | — | US | claimed |
| US-5098922-A | Anticonvulsants | CIBA-GEIGY CORPORATION (US) | 1992-03-24 | — | — | US | disclosed |
| US-5045556-A | Aralkyl-4H-1,2,4-triazole derivatives | CIBA-GEIGY CORPORATION (US) | 1991-09-03 | — | — | US | disclosed |