Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MPL | P40238 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733835 | 0.85 | ALDH1A1 (0.57) | ALDH1A1MAPTLMNACYP2C19GAA | |
| SCHEMBL9733308 | 0.85 | ALDH1A1 (0.45) | ALDH1A1POLBMAPTLMNACYP2C19 | |
| SCHEMBL9733819 | 0.84 | L3MBTL1 (0.46) | ALDH1A1MAPTLMNACYP2C19GAA | |
| SCHEMBL9733191 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNACYP2C19CYP1A2 | |
| SCHEMBL9734019 | 0.83 | ALDH1A1 (0.59) | ALDH1A1POLBMAPTLMNACYP2C19 | |
| SCHEMBL9733469 | 0.81 | MAPT (0.44) | ALDH1A1POLBMAPTLMNACYP2C19 | |
| SCHEMBL9733338 | 0.81 | CA2 (0.47) | ALDH1A1MAPTLMNACYP2C19CYP2D6 | |
| SCHEMBL9734920 | 0.80 | ALDH1A1 (0.57) | ALDH1A1POLBMAPTLMNACYP2C19 | |
| SCHEMBL9734089 | 0.80 | GRM5 (0.50) | ALDH1A1POLBMAPTLMNACYP2C19 | |
| SCHEMBL9733344 | 0.75 | ALDH1A1 (0.44) | ALDH1A1POLBMAPTCYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124331-A | Anticancer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0364598-A1 | 3,4-dihydrothieno ¬2,3-d pyrimidine compounds and pharmaceutical application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-25 | — | — | EP | disclosed |