Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734017 | 0.87 | ALDH1A1 (0.48) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL9734163 | 0.86 | HIF1A (0.48) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL9734943 | 0.83 | HIF1A (0.44) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL9733959 | 0.81 | ALDH1A1 (0.56) | MAPTKMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9733292 | 0.79 | MEN1 (0.45) | KMT2AMEN1ALDH1A1HIF1ACYP2C19 | |
| SCHEMBL9733574 | 0.77 | KMT2A (0.45) | KMT2AMEN1ALDH1A1HIF1ALMNA | |
| SCHEMBL9733634 | 0.76 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1HIF1ALMNA | |
| SCHEMBL9733389 | 0.72 | ALDH1A1 (0.42) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL9733681 | 0.71 | ALDH1A1 (0.45) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9737918 | 0.71 | ALDH1A1 (0.62) | MAPTALDH1A1HIF1ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124331-A | Anticancer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0364598-A1 | 3,4-dihydrothieno ¬2,3-d pyrimidine compounds and pharmaceutical application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-25 | — | — | EP | disclosed |