Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | HTR2B | P41595 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907219 | 0.78 | HSP90AA1 (0.49) | MAPK1MAPTHSP90AA1AHRALDH1A1 | |
| SCHEMBL29455135 | 0.78 | AHR (0.52) | MAPK1AHRALDH1A1 | |
| SCHEMBL4450440 | 0.78 | AHR (0.52) | MAPK1AHRALDH1A1 | |
| SCHEMBL7904037 | 0.73 | AHR (0.42) | MAPK1KDM4EAHRHTR2AHTR2C | |
| SCHEMBL7905156 | 0.72 | AHR (0.46) | MAPK1MAPTHSP90AA1KDM4EAHR | |
| SCHEMBL7897846 | 0.71 | MAPK1 (0.57) | MAPK1MAPTHSP90AA1NPSR1KDM4E | |
| SCHEMBL9732658 | 0.71 | MAPK1 (0.57) | MAPK1MAPTHSP90AA1NPSR1RAB9A | |
| SCHEMBL9732232 | 0.71 | AHR (0.57) | MAPK1MAPTHSP90AA1NPSR1RAB9A | |
| SCHEMBL30715275 | 0.71 | ALDH1A1 (0.46) | MAPK1MAPTHSP90AA1NPSR1KDM4E | |
| SCHEMBL53547 | 0.71 | ALDH1A1 (0.46) | MAPK1MAPTHSP90AA1NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145790-A | Immunoassay, fluorescein derivative | ABBOTT LABORATORIES (US) | 1992-09-08 | — | — | US | disclosed |
| EP-0455058-A2 | Reagents and method for detecting polychlorinated biphenyls | ABBOTT LABORATORIES (US) | 1991-11-06 | — | — | EP | disclosed |