Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734016 | 0.73 | MAPK1 (0.41) | AHRMAPK1ALDH1A1KDM4EHTR2C | |
| SCHEMBL7907219 | 0.73 | HSP90AA1 (0.49) | AHRMAPK1ALDH1A1CHEK1 | |
| SCHEMBL27960290 | 0.72 | ALDH1A1 (0.56) | MAPK1ALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL29455135 | 0.72 | AHR (0.52) | AHRMAPK1ALDH1A1HSD17B10TSHR | |
| SCHEMBL4450440 | 0.72 | AHR (0.52) | AHRMAPK1ALDH1A1HSD17B10TSHR | |
| SCHEMBL4842699 | 0.70 | ALDH1A1 (0.45) | MAPK1ALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL29370249 | 0.69 | AHR (0.55) | AHRMAPK1ALDH1A1TSHR | |
| SCHEMBL4453300 | 0.69 | AHR (0.55) | AHRMAPK1ALDH1A1TSHR | |
| SCHEMBL4657348 | 0.68 | ALDH1A1 (0.48) | MAPK1ALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL13843510 | 0.67 | CYP2A6 (0.48) | MAPK1ALDH1A1KDM4EHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204005-B1 | ACCURATE AND SENSITIVE QUALITATIVE OR QUANTITATIVE ANALYSIS BY INCUBATING ANTIBODIES AND COMPETITOR OF DEFINED STRUCTURE IN PRESENCE OF TEST SAMPLE, THEN DETECTING CONGENER | ECOCHEM RESEARCH, INC. | 2001-03-20 | — | — | US | disclosed |
| US-5538852-A | QUALITATIVE OR QUANTITATIVE ANALYSIS WITH COMPETITORS AND ANTIBODIES | ECOCHEM RESEARCH, INC. (US) | 1996-07-23 | — | — | US | disclosed |