Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | CPN1 | P15169 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | SLC6A1 | P30531 | 4/20 | 0.38 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.38 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | GLI1 | P08151 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732477 | 0.89 | NAAA (0.50) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9731779 | 0.83 | SLC6A1 (0.47) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL28865044 | 0.81 | KMT2A (0.56) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6050295 | 0.81 | KMT2A (0.56) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL5232333 | 0.79 | KMT2A (0.40) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL13308547 | 0.79 | KMT2A (0.62) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL2525645 | 0.79 | KMT2A (0.62) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL13308548 | 0.79 | KMT2A (0.62) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7470707 | 0.79 | ITGB3 (0.41) | CPN1CPB2DPP4SLC6A1SLC6A11 | |
| SCHEMBL24127567 | 0.78 | HPGD (0.48) | KMT2ADPP4ATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147882-A | Cardiovascular disorders | KARL THOMAE GMBH (DE) | 1992-09-15 | — | — | US | disclosed |
| EP-0450429-A1 | Cyclophanes, process for their preparation and pharmaceuticals containing them | Dr. Karl Thomae GmbH (DE) | 1991-10-09 | — | — | EP | disclosed |