Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.37 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
| ▸ | TOP1 | P11387 | 2/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | PDCD4 | Q53EL6 | 3/20 | 0.33 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.33 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.33 |
| ▸ | TST | Q16762 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734932 | 0.82 | PDCD4 (0.41) | DAGLAPDCD4PPARG | |
| SCHEMBL9735225 | 0.70 | TOP1 (0.40) | DAGLATOP1PDCD4 | |
| SCHEMBL8616760 | 0.63 | PDCD4 (0.42) | DAGLAPDCD4 | |
| SCHEMBL4100839 | 0.62 | HIF1A (0.50) | — | |
| SCHEMBL7290380 | 0.59 | GPR84 (0.56) | ZDHHC7MAPT | |
| SCHEMBL28631358 | 0.59 | GPR84 (0.56) | ZDHHC7MAPT | |
| SCHEMBL6434519 | 0.59 | GPR84 (0.56) | ZDHHC7MAPT | |
| SCHEMBL3175045 | 0.59 | — | — | |
| SCHEMBL6651887 | 0.59 | GPR84 (0.56) | ZDHHC7MAPT | |
| SCHEMBL8363305 | 0.59 | GPR84 (0.56) | ZDHHC7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134128-A | Immunosuppressive and antiproliferative activity for psoriasis and calcium homeostasis | ALLERGAN, INC. (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0295056-A1 | Anti-inflammatory furanones | ALLERGAN, INC (US) | 1988-12-14 | — | — | EP | disclosed |