Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 16/20 | 0.56 |
| ▸ | HRH1 | P35367 | 16/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736188 | 0.95 | KDM4E (0.54) | HRH2HRH1DRD2KDM4E | |
| SCHEMBL9734342 | 0.88 | HRH2 (0.55) | HRH2HRH1DRD2HRH3 | |
| SCHEMBL9736225 | 0.83 | KDM4E (0.51) | KDM4E | |
| SCHEMBL9734398 | 0.83 | KCNA5 (0.55) | HRH2HRH1DRD2HRH3 | |
| SCHEMBL9734416 | 0.80 | KCNA5 (0.56) | HRH2HRH1DRD2 | |
| SCHEMBL9734873 | 0.77 | KDM4E (0.57) | DRD2KDM4E | |
| SCHEMBL7251399 | 0.77 | HRH2 (0.77) | HRH2HRH1HRH3 | |
| SCHEMBL7245508 | 0.77 | HRH2 (0.77) | HRH2HRH1HRH3 | |
| SCHEMBL2089311 | 0.76 | KDM4E (0.78) | HRH2HRH1DRD2HRH3KDM4E | |
| SCHEMBL491928 | 0.75 | KDM4E (0.81) | HRH2HRH1HRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |