Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CHKA | P35790 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735099 | 0.87 | POLB (0.53) | KDM4EGAAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8824257 | 0.85 | L3MBTL1 (0.62) | KDM4EMAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9735532 | 0.84 | PARP1 (0.49) | KDM4EKMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL9736188 | 0.83 | KDM4E (0.54) | KDM4EMAPT | |
| SCHEMBL9735095 | 0.83 | PARP1 (0.51) | — | |
| SCHEMBL9734496 | 0.83 | KMT2A (0.53) | KDM4EMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9734811 | 0.83 | HRH2 (0.56) | KDM4E | |
| SCHEMBL23632237 | 0.79 | L3MBTL1 (0.67) | KDM4EGAAMEN1KMT2AMAPT | |
| SCHEMBL18074822 | 0.76 | ALDH1A1 (0.67) | KDM4EGAAMEN1KMT2AMAPT | |
| SCHEMBL9736208 | 0.75 | SMN1; SMN2 (0.62) | KDM4EGAAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |