Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | LTA4H | P09960 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734416 | 0.92 | KCNA5 (0.56) | LTA4HALDH1A1DRD2DRD3PKM | |
| SCHEMBL9734398 | 0.85 | KCNA5 (0.55) | DRD2DRD3KCNA5 | |
| SCHEMBL9736188 | 0.82 | KDM4E (0.54) | KDM4EDRD2DRD3KCNA5 | |
| SCHEMBL9734342 | 0.81 | HRH2 (0.55) | DRD2KCNA5 | |
| SCHEMBL9735958 | 0.80 | KCNA5 (0.53) | KDM4EALDH1A1SMN1; SMN2L3MBTL1DRD2 | |
| SCHEMBL9734496 | 0.79 | KMT2A (0.53) | KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9734538 | 0.79 | SMN1; SMN2 (0.56) | HTTNPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL13780326 | 0.79 | SMN1; SMN2 (0.56) | HTTNPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL9734811 | 0.77 | HRH2 (0.56) | KDM4EDRD2 | |
| SCHEMBL9737216 | 0.76 | SMN1; SMN2 (0.48) | KDM4EHTTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |