Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 15/20 | 0.55 |
| ▸ | HRH1 | P35367 | 15/20 | 0.55 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734398 | 0.95 | KCNA5 (0.55) | HRH2HRH1KCNA5HRH3DRD2 | |
| SCHEMBL9734811 | 0.88 | HRH2 (0.56) | HRH2HRH1HRH3DRD2 | |
| SCHEMBL9734416 | 0.84 | KCNA5 (0.56) | HRH2HRH1KCNA5DRD2 | |
| SCHEMBL9736188 | 0.82 | KDM4E (0.54) | HRH2HRH1KCNA5DRD2 | |
| SCHEMBL9734873 | 0.81 | KDM4E (0.57) | KCNA5DRD2 | |
| SCHEMBL8824257 | 0.80 | L3MBTL1 (0.62) | HRH3 | |
| SCHEMBL10200150 | 0.76 | DRD3 (0.68) | HRH2HRH1KCNA5HRH3DRD2 | |
| SCHEMBL7245508 | 0.76 | HRH2 (0.77) | HRH2HRH1HRH3 | |
| SCHEMBL7251399 | 0.76 | HRH2 (0.77) | HRH2HRH1HRH3 | |
| SCHEMBL9735965 | 0.76 | PKM (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |