Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 11/20 | 0.51 |
| ▸ | DRD2 | P14416 | 6/20 | 0.51 |
| ▸ | HRH2 | P25021 | 4/20 | 0.50 |
| ▸ | HRH1 | P35367 | 4/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734811 | 0.95 | HRH2 (0.56) | KDM4EDRD2HRH2HRH1 | |
| SCHEMBL9734398 | 0.88 | KCNA5 (0.55) | DRD3DRD2HRH2HRH1KCNA5 | |
| SCHEMBL9734416 | 0.85 | KCNA5 (0.56) | DRD3DRD2HRH2HRH1KCNA5 | |
| SCHEMBL9736225 | 0.83 | KDM4E (0.51) | KDM4EMAPT | |
| SCHEMBL9734342 | 0.82 | HRH2 (0.55) | DRD2HRH2HRH1KCNA5 | |
| SCHEMBL9734873 | 0.82 | KDM4E (0.57) | KDM4EDRD3DRD2KCNA5 | |
| SCHEMBL9735958 | 0.76 | KCNA5 (0.53) | KDM4EDRD3DRD2KCNA5 | |
| SCHEMBL2229668 | 0.75 | KDM4E (0.90) | KDM4EDRD3DRD2MAPT | |
| SCHEMBL9734991 | 0.75 | HPGD (0.55) | DRD3DRD2 | |
| SCHEMBL5681637 | 0.74 | KDM4E (0.92) | KDM4EHRH2HRH1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |