Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084217 | 0.87 | ALOX5 (0.40) | ALOX5RAB9ASMN1; SMN2NPC1CTDSP1 | |
| SCHEMBL9737036 | 0.84 | NPSR1 (0.32) | MAPTKDM4E | |
| SCHEMBL9735328 | 0.82 | MAOB (0.33) | — | |
| SCHEMBL9737279 | 0.82 | CHRM2 (0.34) | RAB9ANPC1MAPTCASP3POLB | |
| SCHEMBL9738703 | 0.80 | CNR2 (0.38) | ALOX5RAB9ASMN1; SMN2NPC1CTDSP1 | |
| SCHEMBL9736905 | 0.80 | ALOX5 (0.39) | ALOX5RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL8090664 | 0.79 | MAPT (0.46) | RAB9ASMN1; SMN2CTDSP1MAPTKDM4E | |
| SCHEMBL9732982 | 0.78 | ALOX5 (0.38) | ALOX5RAB9ASMN1; SMN2NPC1CTDSP1 | |
| SCHEMBL9737143 | 0.78 | ALDH1A1 (0.36) | RAB9ASMN1; SMN2NPC1MAPTKDM4E | |
| SCHEMBL7268034 | 0.76 | ALOX5 (0.40) | ALOX5RAB9ASMN1; SMN2NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |