Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.32 |
| ▸ | ICMT | O60725 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737036 | 0.85 | NPSR1 (0.32) | MAOBCYP3A4 | |
| SCHEMBL7267575 | 0.84 | ABCC9 (0.37) | MAOBABCB1MALT1ABCC9HTR1A | |
| SCHEMBL9737279 | 0.82 | CHRM2 (0.34) | MALT1HTR1A | |
| SCHEMBL9734818 | 0.82 | ALOX5 (0.36) | — | |
| SCHEMBL9194883 | 0.79 | PDE4A (0.36) | MAOBABCB1MALT1PDE4APDE4B | |
| SCHEMBL8090669 | 0.79 | MALT1 (0.36) | MALT1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8088358 | 0.78 | MALT1 (0.35) | MALT1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9735762 | 0.78 | ABCC9 (0.42) | MAOBABCB1MALT1PDE4APDE4B | |
| SCHEMBL9147323 | 0.77 | ABCB1 (0.33) | MAOBABCB1PDE4APDE4BPDE4C | |
| SCHEMBL9148650 | 0.77 | ABCC9 (0.33) | MAOBABCB1MALT1ABCC9HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |