Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737735 | 0.89 | S100A4 (0.35) | RAB9ASMN1; SMN2NPC1FGFR1ALDH1A1 | |
| SCHEMBL8084217 | 0.87 | ALOX5 (0.40) | CNR2ALOX5CNR1RAB9ASMN1; SMN2 | |
| SCHEMBL9732982 | 0.84 | ALOX5 (0.38) | CNR2ALOX5CNR1RAB9ASMN1; SMN2 | |
| SCHEMBL9733518 | 0.82 | FTO (0.31) | SMN1; SMN2 | |
| SCHEMBL9147909 | 0.82 | NR1H4 (0.33) | MAPT | |
| SCHEMBL9733560 | 0.82 | ALDH1A1 (0.39) | RAB9ASMN1; SMN2NPC1MAPTPDK2 | |
| SCHEMBL9734818 | 0.80 | ALOX5 (0.36) | CNR2ALOX5CNR1RAB9ASMN1; SMN2 | |
| SCHEMBL9734520 | 0.80 | — | — | |
| SCHEMBL9732962 | 0.80 | MAPT (0.35) | RAB9ASMN1; SMN2NPC1MAPTCASP3 | |
| SCHEMBL9369702 | 0.80 | ABCC9 (0.35) | CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143924-A | OXODIHYDROPYRIDYL CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |