Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734538 | 0.97 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9ACYP2C19MEN1 | |
| SCHEMBL13780326 | 0.97 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9ACYP2C19MEN1 | |
| SCHEMBL9737216 | 0.89 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9ACYP2C19MEN1 | |
| SCHEMBL16611411 | 0.80 | MEN1 (0.69) | SMN1; SMN2NPC1RAB9ACYP2C19MEN1 | |
| SCHEMBL5109854 | 0.79 | MEN1 (0.71) | SMN1; SMN2NPC1RAB9ACYP2C19MEN1 | |
| SCHEMBL7955572 | 0.79 | NAMPT (0.48) | SMN1; SMN2MEN1KMT2APARP1NAMPT | |
| SCHEMBL9737233 | 0.79 | L3MBTL1 (0.53) | MEN1KMT2AGAANAMPTHTT | |
| SCHEMBL9734496 | 0.79 | KMT2A (0.53) | SMN1; SMN2CYP2C19MEN1KMT2ANAMPT | |
| SCHEMBL9736168 | 0.78 | TPSAB1 (0.55) | SMN1; SMN2MEN1KMT2AGAADPP4 | |
| Hydrochloric Acid SCHEMBL29864758 | 0.78 | MEN1 (0.69) | SMN1; SMN2NPC1RAB9ACYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |