Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734538 | 0.92 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9ACYP2C19KMT2A | |
| SCHEMBL13780326 | 0.92 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9ACYP2C19KMT2A | |
| SCHEMBL9734867 | 0.89 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9ACYP2C19KMT2A | |
| SCHEMBL9737233 | 0.79 | L3MBTL1 (0.53) | KMT2AMEN1NAMPTGAAALDH1A1 | |
| SCHEMBL9734496 | 0.79 | KMT2A (0.53) | SMN1; SMN2CYP2C19KMT2AMEN1NAMPT | |
| SCHEMBL9734807 | 0.79 | GAA (0.46) | SMN1; SMN2KMT2AMEN1PARP1NAMPT | |
| SCHEMBL9735768 | 0.78 | GAA (0.49) | SMN1; SMN2KMT2AMEN1PARP1NAMPT | |
| SCHEMBL9735396 | 0.78 | GAA (0.51) | SMN1; SMN2MEN1PARP1NAMPTGAA | |
| SCHEMBL13780266 | 0.78 | ALDH1A1 (0.59) | SMN1; SMN2NPC1RAB9ACYP2C19KMT2A | |
| SCHEMBL9736168 | 0.78 | TPSAB1 (0.55) | SMN1; SMN2KMT2AMEN1NAMPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |