SCHEMBL9737233

SCHEMBL9737233

O=C1CCC(C(=O)N2CCN(C(=O)Cc3ccccc3)CC2)N1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.53
ALDH1A1 P00352 6/20 0.53
KDM4E B2RXH2 3/20 0.53
HSD11B1 P28845 1/20 0.50
NAMPT P43490 2/20 0.49
MAPT P10636 1/20 0.49
PKM P14618 1/20 0.49
ALOX12 P18054 1/20 0.49
USP2 O75604 1/20 0.48
GAA P10253 1/20 0.48
TSHR P16473 1/20 0.48
ME2 P23368 2/20 0.47
ME1 P48163 2/20 0.47
ME3 Q16798 2/20 0.47
TACR3 P29371 1/20 0.47
POLB P06746 1/20 0.47
TPSAB1 Q15661 1/20 0.47
TPSD1 Q9BZJ3 1/20 0.47
TPSG1 Q9NRR2 1/20 0.47
MEN1 O00255 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9734613 0.88 GFER (0.50) ALDH1A1HSD11B1NAMPTME2ME1
SCHEMBL9734496 0.85 KMT2A (0.53) ALDH1A1KDM4ENAMPTTSHRPOLB
SCHEMBL9736216 0.84 SMN1; SMN2 (0.64) L3MBTL1ALDH1A1KDM4EMAPTGAA
SCHEMBL9734863 0.82 CYP2C9 (0.56) L3MBTL1ALDH1A1GAATACR3MEN1
SCHEMBL9734538 0.81 SMN1; SMN2 (0.56) L3MBTL1NAMPTGAAMEN1HTT
SCHEMBL13780326 0.81 SMN1; SMN2 (0.56) L3MBTL1NAMPTGAAMEN1HTT
SCHEMBL9735387 0.80 NAMPT (0.67) ALDH1A1NAMPTMAPTUSP2TSHR
SCHEMBL9734952 0.80 NAMPT (0.52) L3MBTL1ALDH1A1KDM4ENAMPTUSP2
SCHEMBL7950882 0.80 NAMPT (0.51) L3MBTL1ALDH1A1NAMPTTSHRPOLB
SCHEMBL7950888 0.80 NAMPT (0.51) L3MBTL1ALDH1A1NAMPTTSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5102882-A Nootropic agents NIPPON SHINYAKU CO., LTD. (JP) 1992-04-07 US disclosed