Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.64 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.60 |
| ▸ | LGMN | Q99538 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30443433 | 1.00 | KEAP1 (0.64) | KEAP1ADRA2CLGMNGAAMEN1 | |
| Hydrochloric Acid SCHEMBL9424019 | 0.98 | KEAP1 (0.62) | KEAP1ADRA2CLGMNGAAMEN1 | |
| Hydrochloric Acid SCHEMBL23536416 | 0.98 | KEAP1 (0.62) | KEAP1ADRA2CLGMNGAAMEN1 | |
| Aniline SCHEMBL22169106 | 0.93 | LGMN (0.57) | KEAP1ADRA2CLGMNGAAMEN1 | |
| SCHEMBL3434299 | 0.93 | KEAP1 (0.67) | KEAP1ADRA2CLGMNGAAMEN1 | |
| SCHEMBL9424119 | 0.84 | LMNA (0.62) | LGMNGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23152040 | 0.84 | ADRA2C (0.79) | KEAP1ADRA2CLGMNGAAMEN1 | |
| SCHEMBL11775877 | 0.84 | ADRA2C (0.79) | KEAP1ADRA2CLGMNGAAMEN1 | |
| SCHEMBL904453 | 0.84 | LGMN (0.51) | KEAP1ADRA2CLGMNGAAMEN1 | |
| SCHEMBL31248708 | 0.84 | LGMN (0.51) | KEAP1ADRA2CLGMNGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1626 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117186472-A | High-temperature-resistant stretch-resistant colorful film and preparation method thereof | 新航涂布科技(苏州)有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-104974149-B | A kind of preparation method of razaxaban | 北大方正集团有限公司 | 2018-05-01 | — | — | CN | claimed |
| CN-104974148-B | The method of one kind synthesis ketone of 4 { 4 [base of 1,3 oxazolidine of (5S) 5 (amino methyl) 2 oxo 3] phenyl } morpholine 3 | 北大方正集团有限公司 | 2017-11-24 | — | — | CN | claimed |
| CN-105085507-B | A kind of method for synthesizing razaxaban | 北大方正集团有限公司 | 2017-11-24 | — | — | CN | claimed |
| EP-2611797-B1 | QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS | HANMI SCIENCE CO LTD (KR) | 2016-12-28 | — | — | EP | claimed |
| US-8835458-B2 | Quinoline or quinazoline derivatives with apoptosis inducing activity on cells | HANMI SCIENCE CO., LTD (KR) | 2014-09-16 | — | — | US | claimed |
| EP-2611797-A2 | QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS | Hanmi Science Co., Ltd. (KR) | 2013-07-10 | — | — | EP | claimed |
| US-20130165386-A1 | QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS | HANMI SCIENCE CO., LTD (KR) | 2013-06-27 | — | — | US | claimed |
| WO-2012030160-A2 | QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS | HANMI HOLDINGS CO., LTD. (KR) | 2012-03-08 | — | — | WO | claimed |
| US-8043385-B2 | Composition oxidation colouring of keratinic fibres, containing a cationic cellulose ether, a metasilicate and oxidation dyes, method for oxidation colouring and uses thereof | L'OREAL S.A. (FR) | 2011-10-25 | — | — | US | claimed |
| US-4692166-A | OXIDATION COLOR DYES USED WITH DIAMINOBENZENES OR AMINO PHENOLS; MINIMIZATION OF RED HUE | L'OREAL (FR) | 1987-09-08 | — | — | US | claimed |
| US-4563188-A | SHADES OF GREEN | L'OREAL (FR) | 1986-01-07 | — | — | US | claimed |
| US-4425132-A | HAIR DYES, APPLYING WITHOUT RINSING | L'OREAL (FR) | 1984-01-10 | — | — | US | claimed |
| US-4337061-A | NITRO DYES IN AQUEOUS SOLUTION | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-06-29 | — | — | US | claimed |
| US-4323360-A | Dyeing compositions for hair which contain 2,4-diamino-butoxybenzene and/or a salt thereof as the coupling agent | L'OREAL (FR) | 1982-04-06 | — | — | US | claimed |
| US-4289495-A | HAIR DYES, STORAGE STABILITY | L'OREAL (FR) | 1981-09-15 | — | — | US | claimed |
| US-4200432-A | HAIR DYES | L'OREAL (FR) | 1980-04-29 | — | — | US | claimed |
| US-4149848-A | N-/TETRAHYDROFURFURYL/P-PHENYLENEDIAMINES | L'OREAL (FR) | 1979-04-17 | — | — | US | claimed |
| US-3961879-A | P-PHENYLENEDIAMINE, HAIR | L'OREAL (FR) | 1976-06-08 | — | — | US | claimed |
| US-3948596-A | Oxidation dye for keratinic fibers containing 2-halo-5-acetaminophenol as a coupler | SOCIETE ANONYME DITE: L'OREAL (FR) | 1976-04-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165386-A1 | QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS | CASP7, API5, BAX | KEAP1 475/4885ADRA2C 4016/4885LGMN 3300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.