Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735545 | 0.86 | — | — | |
| SCHEMBL9737765 | 0.84 | ABCB1 (0.38) | MEN1KMT2A | |
| SCHEMBL9736949 | 0.84 | MAPT (0.32) | SMN1; SMN2MEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL9736521 | 0.83 | AXL (0.32) | ALOX5IDO1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9736085 | 0.82 | IDO1 (0.34) | ALOX5IDO1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9735767 | 0.81 | ALOX5 (0.33) | ALOX5SMN1; SMN2RARBRARGMAPT | |
| SCHEMBL9735212 | 0.79 | CA12 (0.34) | ALOX5IDO1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9735222 | 0.75 | RARB (0.33) | ALOX5IDO1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7331735 | 0.72 | ABCB1 (0.39) | — | |
| SCHEMBL7334077 | 0.71 | ALOX5 (0.34) | ALOX5SMN1; SMN2MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |
| EP-0415065-A1 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |