Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735545 | 0.86 | — | — | |
| SCHEMBL9737765 | 0.84 | ABCB1 (0.38) | MEN1KMT2A | |
| SCHEMBL9735313 | 0.84 | ALOX5 (0.32) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9735242 | 0.83 | MAPT (0.33) | MAPTLMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL9735535 | 0.82 | KMT2A (0.36) | MAPTLMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL9738453 | 0.81 | LMNA (0.33) | MAPTLMNAHTTSMN1; SMN2CACNA1C | |
| SCHEMBL9737027 | 0.79 | AKR1B1 (0.34) | MAPTLMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9737038 | 0.74 | AKR1B1 (0.33) | MAPTLMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7331735 | 0.70 | ABCB1 (0.39) | LMNA | |
| SCHEMBL9740284 | 0.70 | ALDH1A1 (0.33) | MAPTLMNAHTTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |
| EP-0415065-A1 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |