Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | RARG | P13631 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 2/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735711 | 0.88 | ALDH1A1 (0.31) | MEN1KMT2ATSHRPOLBALDH1A1 | |
| SCHEMBL9737038 | 0.84 | AKR1B1 (0.33) | SMN1; SMN2EDNRAMAPTLMNAEDNRB | |
| SCHEMBL9735704 | 0.84 | ABCC9 (0.38) | MEN1KMT2ALMNA | |
| SCHEMBL9737251 | 0.83 | HSD17B10 (0.34) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL9735212 | 0.80 | CA12 (0.34) | RARBRARGRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9736521 | 0.76 | AXL (0.32) | SMN1; SMN2MEN1KMT2AALOX5MAPT | |
| SCHEMBL9735767 | 0.75 | ALOX5 (0.33) | RARBRARGRAB9ASMN1; SMN2ALOX5 | |
| SCHEMBL9735313 | 0.75 | ALOX5 (0.32) | RARBRARGRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9735900 | 0.74 | OPRD1 (0.34) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL9735947 | 0.74 | ABCC9 (0.39) | RARBRARGRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |
| EP-0415065-A1 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |