Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 2/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735602 | 0.86 | ABCC9 (0.41) | ABCC9ABCC8KCNJ11KCNJ8LMNA | |
| SCHEMBL9147952 | 0.85 | ABCC9 (0.43) | ABCC9ABCC8KCNJ11KCNJ8LMNA | |
| SCHEMBL9735333 | 0.83 | ABCC9 (0.59) | ABCC9ABCC8KCNJ11KCNJ8LMNA | |
| SCHEMBL9735947 | 0.83 | ABCC9 (0.39) | ABCC9ABCC8KCNJ11KCNJ8LMNA | |
| SCHEMBL9734741 | 0.82 | ABCC9 (0.52) | ABCC9ABCC8KCNJ11KCNJ8LMNA | |
| SCHEMBL9740284 | 0.80 | ALDH1A1 (0.33) | ABCC9LMNAALDH1A1L3MBTL1KMT2A | |
| SCHEMBL9737027 | 0.75 | AKR1B1 (0.34) | LMNAALDH1A1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL9130634 | 0.74 | ABCC9 (0.67) | ABCC9ABCC8KCNJ11KCNJ8LMNA | |
| SCHEMBL9130626 | 0.74 | ABCC9 (0.67) | ABCC9ABCC8KCNJ11KCNJ8LMNA | |
| SCHEMBL9130641 | 0.74 | ABCC9 (0.67) | ABCC9ABCC8KCNJ11KCNJ8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |