Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 2/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735602 | 0.86 | ABCC9 (0.41) | ABCC9ABCC8KCNJ11KCNJ8LMNA | |
| SCHEMBL9735333 | 0.83 | ABCC9 (0.59) | ABCC9ABCC8KCNJ11KCNJ8LMNA | |
| SCHEMBL9735385 | 0.83 | ABCC9 (0.39) | ABCC9ABCC8KCNJ11KCNJ8LMNA | |
| SCHEMBL9736829 | 0.82 | ABCC9 (0.52) | ABCC9ABCC8KCNJ11KCNJ8LMNA | |
| SCHEMBL9735486 | 0.80 | ALOX5 (0.36) | LMNAHSD17B10ALDH1A1HPGDIDO1 | |
| SCHEMBL10913246 | 0.77 | ABCC9 (0.65) | ABCC9ABCC8KCNJ11KCNJ8LMNA | |
| SCHEMBL10913242 | 0.77 | ABCC9 (0.65) | ABCC9ABCC8KCNJ11KCNJ8LMNA | |
| SCHEMBL10913244 | 0.77 | ABCC9 (0.65) | ABCC9ABCC8KCNJ11KCNJ8LMNA | |
| SCHEMBL9735212 | 0.75 | CA12 (0.34) | LMNAHSD17B10IDO1RARBRARG | |
| SCHEMBL9735222 | 0.74 | RARB (0.33) | LMNAALOX15HSD17B10ALDH1A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |
| EP-0415065-A1 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |