Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25975033 | 0.85 | NT5E (0.47) | HSD11B1KDM4EHPGD | |
| SCHEMBL3586547 | 0.81 | ALDH1A1 (0.44) | GUSBPTGS1PTGS2CXCR2HSD11B1 | |
| SCHEMBL8178007 | 0.80 | CNR1 (0.40) | GUSBPTGS1PTGS2HSD11B1ALDH1A1 | |
| SCHEMBL27731900 | 0.77 | KDM4E (0.45) | PTGS1PTGS2ALDH1A1KDM4EHPGD | |
| SCHEMBL7144947 | 0.77 | HSP90AA1 (0.47) | GUSBCXCR2HSD11B1NPBWR1HSP90AA1 | |
| SCHEMBL31254967 | 0.76 | ALDH1A1 (0.44) | ALDH1A1KDM4EHTTLMNAKMT2A | |
| SCHEMBL27663798 | 0.75 | GAA (0.46) | PTGS1PTGS2CXCR2ALDH1A1KDM4E | |
| SCHEMBL5442233 | 0.74 | IDO1 (0.36) | ALDH1A1KDM4EGAAHSD17B10 | |
| SCHEMBL27933325 | 0.74 | DGAT1 (0.35) | — | |
| SCHEMBL3803127 | 0.72 | JAK2 (0.36) | GUSBALDH1A1KDM4EAHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007835-A1 | IMIDAZOLE FUNGICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-05-14 | — | — | WO | disclosed |