Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TLR3 | O15455 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736485 | 0.86 | IDO1 (0.32) | SMN1; SMN2 | |
| SCHEMBL9735910 | 0.83 | ABCC9 (0.42) | KMT2AMEN1LMNAABCC9 | |
| SCHEMBL9736573 | 0.83 | MAPT (0.36) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL9736949 | 0.82 | MAPT (0.32) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL9735568 | 0.80 | MAPT (0.35) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL9737706 | 0.79 | TLR3 (0.35) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL7965091 | 0.77 | TLR3 (0.40) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL9739194 | 0.75 | MAPT (0.35) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL8538165 | 0.75 | MAPT (0.35) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL9737720 | 0.74 | TLR3 (0.34) | KMT2AMEN1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |
| EP-0415065-A1 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |