Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734952 | 0.86 | NAMPT (0.52) | POLBALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL9763711 | 0.80 | PKM (0.74) | POLBPKMMAPK1ALDH1A1KMT2A | |
| SCHEMBL9734377 | 0.80 | HPGD (0.54) | KMT2AMEN1HPGDHTTL3MBTL1 | |
| SCHEMBL9735854 | 0.79 | KMT2A (0.58) | POLBALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL9736472 | 0.79 | HSD11B1 (0.51) | POLBALDH1A1KMT2AMEN1GAA | |
| SCHEMBL9735965 | 0.79 | PKM (0.51) | PKMALDH1A1KMT2AMEN1HPGD | |
| Hydrochloric Acid SCHEMBL1596692 | 0.78 | PKM (0.72) | POLBPKMMAPK1ALDH1A1KMT2A | |
| SCHEMBL7950888 | 0.78 | NAMPT (0.51) | POLBALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7950882 | 0.78 | NAMPT (0.51) | POLBALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL27491159 | 0.76 | HPGD (0.65) | POLBPKMMAPK1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |