Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845071 | 0.91 | XIAP (0.33) | XIAPSMN1; SMN2IDO1 | |
| SCHEMBL9737241 | 0.85 | CA12 (0.36) | SMN1; SMN2IDO1MEN1KMT2APOLB | |
| SCHEMBL9736978 | 0.85 | ABCC9 (0.43) | MEN1KMT2A | |
| SCHEMBL9845066 | 0.82 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL9735702 | 0.81 | PBRM1 (0.31) | IDO1PBRM1 | |
| SCHEMBL9736733 | 0.78 | IDO1 (0.34) | XIAPSMN1; SMN2IDO1 | |
| SCHEMBL9736155 | 0.78 | XIAP (0.32) | XIAPSMN1; SMN2IDO1ALDH1A1MEN1 | |
| SCHEMBL9736485 | 0.78 | IDO1 (0.32) | XIAPSMN1; SMN2IDO1 | |
| SCHEMBL9735180 | 0.77 | HTR2B (0.33) | XIAPSMN1; SMN2IDO1ALDH1A1MEN1 | |
| SCHEMBL9845023 | 0.76 | CA12 (0.34) | SMN1; SMN2IDO1ALDH1A1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |