Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735707 | 0.78 | MALT1 (0.33) | NPSR1PBRM1KDM4EMAPTMALT1 | |
| SCHEMBL9737040 | 0.77 | NPSR1 (0.30) | NPSR1 | |
| SCHEMBL9736236 | 0.76 | KDM4E (0.33) | KDM4E | |
| SCHEMBL9735249 | 0.72 | POLB (0.33) | NPSR1PBRM1KDM4EMAPTMALT1 | |
| SCHEMBL9734213 | 0.71 | PBRM1 (0.33) | NPSR1PBRM1MALT1 | |
| SCHEMBL9736148 | 0.68 | XIAP (0.32) | PBRM1 | |
| SCHEMBL9736934 | 0.68 | NPSR1 (0.33) | NPSR1KDM4EMAPT | |
| SCHEMBL8539965 | 0.68 | MAPT (0.43) | NPSR1PBRM1KDM4EMAPT | |
| SCHEMBL9735702 | 0.66 | PBRM1 (0.31) | PBRM1 | |
| SCHEMBL28738550 | 0.65 | PTGS1 (0.35) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |