Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735762 | 0.85 | ABCC9 (0.42) | SMN1; SMN2TSHRMALT1 | |
| SCHEMBL9735261 | 0.85 | NR1H4 (0.38) | SMN1; SMN2TSHRMALT1POLBKDM4E | |
| SCHEMBL9737143 | 0.84 | ALDH1A1 (0.36) | SMN1; SMN2TSHRPOLBNPSR1MAPT | |
| SCHEMBL9735249 | 0.80 | POLB (0.33) | PTGER1TSHRMALT1POLBHSD17B10 | |
| SCHEMBL9737036 | 0.76 | NPSR1 (0.32) | NPSR1MAPTKDM4E | |
| SCHEMBL9737580 | 0.76 | SMN1; SMN2 (0.35) | PTGER1SMN1; SMN2TSHRMALT1POLB | |
| SCHEMBL9733185 | 0.74 | SMN1; SMN2 (0.33) | SMN1; SMN2TSHRMALT1POLBHSD17B10 | |
| SCHEMBL9735707 | 0.72 | MALT1 (0.33) | MALT1NPSR1MAPTKDM4E | |
| SCHEMBL9846729 | 0.70 | BACE1 (0.37) | TSHRMALT1POLBHSD17B10KMT2A | |
| SCHEMBL9147582 | 0.68 | KMT2A (0.40) | SMN1; SMN2TSHRMALT1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |