Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621762 | 0.88 | HPN (0.37) | HPNMAPTALOX15SIRT5ALDH1A1 | |
| SCHEMBL8530578 | 0.77 | ALOX15 (0.49) | HPNMAPTALOX15SIRT5ALDH1A1 | |
| SCHEMBL9736493 | 0.76 | VCAM1 (0.37) | HPNMAPTALOX15SIRT5ALDH1A1 | |
| SCHEMBL9868139 | 0.74 | VCAM1 (0.33) | HPNMAPTALOX15SIRT5ALDH1A1 | |
| SCHEMBL9868145 | 0.73 | VCAM1 (0.36) | HPNMAPTALOX15SIRT5GAA | |
| SCHEMBL9735816 | 0.68 | HPN (0.39) | HPNMAPTALOX15SIRT5ALDH1A1 | |
| SCHEMBL5574415 | 0.67 | ALOX15 (0.45) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL5692187 | 0.66 | ALOX15 (0.63) | HPNMAPTALOX15SIRT5ALDH1A1 | |
| SCHEMBL646924 | 0.66 | ALOX15 (0.63) | HPNMAPTALOX15SIRT5ALDH1A1 | |
| SCHEMBL10817343 | 0.65 | MAPT (0.61) | HPNMAPTALOX15SIRT5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414206-A2 | 2,4,6-Substituted phenol derivatives | SHIONOGI & CO., LTD. (JP) | 1991-02-27 | — | — | EP | disclosed |