Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736109 | 0.80 | CNR2 (0.35) | CNR2CNR1CA12CA9ALOX5 | |
| SCHEMBL9735336 | 0.79 | ALOX5 (0.36) | CNR2CNR1CA12CA9ALOX5 | |
| SCHEMBL9735503 | 0.78 | ALOX5 (0.35) | CNR2CNR1CA12CA9ALOX5 | |
| SCHEMBL9735371 | 0.74 | ALDH1A1 (0.37) | ALOX5RAB9ASMN1; SMN2MAPTPOLB | |
| SCHEMBL9737241 | 0.71 | CA12 (0.36) | CNR2CA12CA9ALOX5RAB9A | |
| SCHEMBL9736905 | 0.71 | ALOX5 (0.39) | CNR2CNR1ALOX5RAB9ASMN1; SMN2 | |
| SCHEMBL9735212 | 0.69 | CA12 (0.34) | CNR2CA12CA9ALOX5RAB9A | |
| SCHEMBL9845023 | 0.65 | CA12 (0.34) | CNR2CA12CA9ALOX5RAB9A | |
| SCHEMBL9443581 | 0.65 | CA12 (0.38) | CNR2CA12CA9ALOX5RAB9A | |
| SCHEMBL670503 | 0.65 | MAPT (0.61) | CA12CA9ALOX5RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |