Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735249 | 0.84 | POLB (0.33) | POLBMAPTNPSR1TSHRKDM4E | |
| SCHEMBL9737143 | 0.82 | ALDH1A1 (0.36) | ALDH1A1HPGDUSP2POLBCASP3 | |
| SCHEMBL9735603 | 0.82 | PDE4A (0.44) | CASP3LMNA | |
| SCHEMBL9735458 | 0.82 | NR1H4 (0.39) | ALDH1A1POLBCASP3MAPTRAB9A | |
| SCHEMBL9736905 | 0.78 | ALOX5 (0.39) | ALDH1A1POLBCASP3MAPTSMN1; SMN2 | |
| SCHEMBL9738536 | 0.76 | ALDH1A1 (0.39) | ALDH1A1HPGDUSP2POLBCASP3 | |
| SCHEMBL10757385 | 0.75 | ALDH1A1 (0.39) | ALDH1A1HPGDUSP2POLBMAPT | |
| SCHEMBL9733029 | 0.74 | ALDH1A1 (0.38) | ALDH1A1HPGDPOLBCASP3MAPT | |
| SCHEMBL9735903 | 0.74 | CNR2 (0.36) | ALDH1A1POLBCASP3MAPTSMN1; SMN2 | |
| SCHEMBL12364945 | 0.72 | PDE4A (0.36) | ALDH1A1HPGDUSP2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |