Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735920 | 0.79 | CCNB2 (0.47) | ALDH1A1L3MBTL1CCNB2CDK1CCNB1 | |
| SCHEMBL22081739 | 0.71 | CYP3A4 (0.48) | TP53CYP3A4ALDH1A1SLC6A4SLC6A3 | |
| SCHEMBL940896 | 0.70 | ALDH1A1 (0.76) | TP53CYP3A4ALDH1A1L3MBTL1 | |
| SCHEMBL9694893 | 0.69 | MAOA (0.52) | ALDH1A1CCNB2CDK1CCNB1GSK3B | |
| SCHEMBL9694527 | 0.69 | MAOB (0.47) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL22032824 | 0.68 | TP53 (0.44) | TP53CYP3A4ALDH1A1SLC6A4SLC6A3 | |
| SCHEMBL22081819 | 0.68 | TP53 (0.44) | TP53CYP3A4ALDH1A1SLC6A4SLC6A3 | |
| SCHEMBL31210281 | 0.67 | OPRM1 (0.59) | ALDH1A1SLC6A4SLC6A3SLC6A2HSD11B2 | |
| SCHEMBL31210280 | 0.67 | OPRM1 (0.59) | ALDH1A1SLC6A4SLC6A3SLC6A2HSD11B2 | |
| SCHEMBL1764806 | 0.66 | DRD2 (0.64) | CYP3A4CCNB2CDK1CCNB1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227270-B1 | HETEROCYCLIC DERIVATIVES AND USE THEREOF | C&C RES LAB (KR) | 2024-11-13 | — | — | EP | disclosed |
| US-10023591-B2 | Heterocyclic derivatives and use thereof | C&C RESEARCH LABORATORIES (KR) | 2018-07-17 | — | — | US | disclosed |
| US-20170320889-A1 | HETEROCYCLIC DERIVATIVES AND USE THEREOF | C&C RESEARCH LABORATORIES (KR) | 2017-11-09 | — | — | US | disclosed |
| EP-3227270-A2 | HETEROCYCLIC DERIVATIVES AND USE THEREOF | C&C Research Laboratories (KR) | 2017-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10023591-B2 | Heterocyclic derivatives and use thereof | STAT3, JAK2, STAT5A | TP53 184/4885CYP3A4 2899/4885ALDH1A1 1646/4885 |
| US-20170320889-A1 | HETEROCYCLIC DERIVATIVES AND USE THEREOF | STAT3, JAK2, STAT5A | TP53 184/4885CYP3A4 2899/4885ALDH1A1 1646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.