Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 3/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24939784 | 0.81 | PIM3 (0.43) | AR | |
| SCHEMBL9737247 | 0.80 | ALDH1A1 (0.62) | ALDH1A1LMNAMAPTHPGDHTT | |
| SCHEMBL9736622 | 0.80 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTHPGDHTT | |
| SCHEMBL9309327 | 0.71 | PIM3 (0.49) | ALDH1A1HPGDKDM4E | |
| SCHEMBL8560334 | 0.70 | TDP1 (0.50) | ALDH1A1LMNAMAPTHPGDHTT | |
| SCHEMBL24939771 | 0.70 | PIM3 (0.44) | — | |
| SCHEMBL9765145 | 0.69 | AR (0.34) | AR | |
| SCHEMBL24939830 | 0.68 | PIM3 (0.64) | ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL2856986 | 0.67 | CES2 (0.72) | ALDH1A1HPGDKDM4ECES2PARP1 | |
| SCHEMBL30271464 | 0.67 | CES2 (0.47) | LMNACES2ARPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169428-A | Tetrahydrophthalimide derivative and herbicide composition containing same | TOSOH CORPORATION (JP) | 1992-12-08 | — | — | US | disclosed |
| EP-0323271-A1 | Tetrahydrophthalimide derivative and herbicide composition containing the same | Tosoh Corporation (JP) | 1989-07-05 | — | — | EP | disclosed |