SCHEMBL9737247

SCHEMBL9737247

NC(=O)c1cc(N2C(=O)C3=C(CCCC3)C2=O)ccc1Cl

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.62
LMNA P02545 1/20 0.62
MAPT P10636 1/20 0.62
HPGD P15428 1/20 0.62
HTT P42858 1/20 0.62
NPSR1 Q6W5P4 1/20 0.62
PPOX P50336 1/20 0.46
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8560334 0.87 TDP1 (0.50) ALDH1A1LMNAMAPTHPGDHTT
SCHEMBL9736622 0.83 ALDH1A1 (0.41) ALDH1A1LMNAMAPTHPGDHTT
SCHEMBL9765179 0.83 PPOX (0.43) ALDH1A1LMNAMAPTHPGDHTT
SCHEMBL11060009 0.82 MEN1 (0.58) ALDH1A1LMNAMAPTHPGDHTT
SCHEMBL9735997 0.80 ALDH1A1 (0.39) ALDH1A1LMNAMAPTHPGDHTT
SCHEMBL7711735 0.79 PPOX (0.47) MAPTPPOXKMT2A
SCHEMBL7163791 0.79 PPOX (0.69) ALDH1A1MAPTPPOXMEN1KMT2A
SCHEMBL11188018 0.77 ALDH1A1 (0.45) ALDH1A1PPOXMEN1KMT2A
SCHEMBL6916218 0.76 ALDH1A1 (0.37) ALDH1A1LMNAMAPTHPGDHTT
SCHEMBL9807518 0.76 PPOX (0.47) ALDH1A1LMNAMAPTPPOXKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5169428-A Tetrahydrophthalimide derivative and herbicide composition containing same TOSOH CORPORATION (JP) 1992-12-08 US disclosed
EP-0323271-A1 Tetrahydrophthalimide derivative and herbicide composition containing the same Tosoh Corporation (JP) 1989-07-05 EP disclosed