Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ME2 | P23368 | 1/20 | 0.49 |
| ▸ | ME1 | P48163 | 1/20 | 0.49 |
| ▸ | ME3 | Q16798 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | GPR183 | P32249 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.43 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737233 | 0.88 | L3MBTL1 (0.53) | ME2ME1ME3KMT2AMEN1 | |
| SCHEMBL9735532 | 0.86 | PARP1 (0.49) | KMT2APARP1GPR183POLBALDH1A1 | |
| SCHEMBL9736216 | 0.85 | SMN1; SMN2 (0.64) | GFERKMT2AMEN1CYP2C9GPR183 | |
| SCHEMBL9735854 | 0.81 | KMT2A (0.58) | KMT2AMEN1PARP1HPGDHSD11B1 | |
| SCHEMBL9736130 | 0.81 | NAMPT (0.61) | GFERKMT2AMEN1HPGDNAMPT | |
| SCHEMBL9735786 | 0.79 | TPSAB1 (0.46) | KMT2AMEN1PARP1NAMPTTPSAB1 | |
| SCHEMBL7950882 | 0.78 | NAMPT (0.51) | KMT2AMEN1PARP1NAMPTTPSAB1 | |
| SCHEMBL7950888 | 0.78 | NAMPT (0.51) | KMT2AMEN1PARP1NAMPTTPSAB1 | |
| SCHEMBL9734790 | 0.76 | TPSAB1 (0.46) | KMT2AMEN1PARP1NAMPTTPSAB1 | |
| SCHEMBL9735095 | 0.76 | PARP1 (0.51) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |