Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | GFER | P55789 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GPR183 | P32249 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735099 | 0.86 | POLB (0.53) | SMN1; SMN2GAAL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL9734613 | 0.85 | GFER (0.50) | HPGDGFERALDH1A1KMT2ACYP2C9 | |
| SCHEMBL9737233 | 0.84 | L3MBTL1 (0.53) | MAPTGAAL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL9734450 | 0.82 | NAMPT (0.58) | SMN1; SMN2MAPTGFERGAAL3MBTL1 | |
| SCHEMBL9734991 | 0.82 | HPGD (0.55) | SMN1; SMN2HPGDGAAL3MBTL1ALDH1A1 | |
| SCHEMBL9735192 | 0.80 | GPR183 (0.58) | SMN1; SMN2MAPTGAAALDH1A1RAB9A | |
| SCHEMBL9735198 | 0.80 | GPR183 (0.58) | SMN1; SMN2MAPTGAAALDH1A1RAB9A | |
| SCHEMBL9734790 | 0.76 | TPSAB1 (0.46) | SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7950882 | 0.75 | NAMPT (0.51) | SMN1; SMN2L3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL7950888 | 0.75 | NAMPT (0.51) | SMN1; SMN2L3MBTL1ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |