Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KDM6A | O15550 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4562515 | 0.83 | NOTUM (0.55) | CYP2C19KDM4EKDM6AKDM4ACYP2C9 | |
| Hydrochloric Acid SCHEMBL30678145 | 0.81 | NOTUM (0.53) | CYP2C19KDM4EKDM6AKDM4ACYP2C9 | |
| SCHEMBL1384364 | 0.77 | KDM4E (0.45) | CYP2C19KDM4EKDM6AKDM4ACYP2C9 | |
| SCHEMBL27922527 | 0.77 | KDM4E (0.45) | CYP2C19KDM4EKDM6AKDM4ACYP2C9 | |
| SCHEMBL16417043 | 0.73 | BRD4 (0.45) | CYP2C19KDM4EKDM6AKDM4ACYP2C9 | |
| SCHEMBL2888240 | 0.71 | TSHR (0.55) | KDM4EALDH1A1SMN1; SMN2MAPTESR2 | |
| SCHEMBL4985228 | 0.68 | PTPN1 (0.55) | KDM4EALDH1A1HTTPOLBMAPT | |
| SCHEMBL7300197 | 0.67 | CES2 (0.46) | CYP2C9ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL16416812 | 0.66 | LMNA (0.50) | ALDH1A1HTTGFERPOLBNPC1 | |
| SCHEMBL31748399 | 0.65 | KDM4E (0.57) | CYP2C19KDM4EKDM6AKDM4ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5160364-A | Thiophene substituted acrylic derivatives; insecticides, plant growth regulators | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-11-03 | — | — | US | disclosed |