Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6951515 | 0.78 | SMN1; SMN2 (0.69) | CES2CES1RECQLSMN1; SMN2HSD17B10 | |
| SCHEMBL50416 | 0.78 | CES2 (0.71) | CES2CES1RECQLALDH1A1KMT2A | |
| SCHEMBL29399311 | 0.78 | CES2 (0.71) | CES2CES1RECQLALDH1A1KMT2A | |
| SCHEMBL3444846 | 0.75 | CES2 (0.68) | CES2CES1RECQLALDH1A1KMT2A | |
| SCHEMBL14528312 | 0.74 | MAPK13 (0.59) | CES2CES1RECQLALDH1A1KMT2A | |
| SCHEMBL8399955 | 0.73 | RORC (0.43) | CES2CES1RECQLSMN1; SMN2HSD17B10 | |
| SCHEMBL27922527 | 0.72 | KDM4E (0.45) | SMN1; SMN2HSD17B10ALDH1A1LMNACYP2C9 | |
| SCHEMBL11404038 | 0.71 | LMNA (0.48) | CES2CES1RECQLALDH1A1CNR2 | |
| SCHEMBL7208739 | 0.70 | RAB9A (0.59) | CES2CES1RECQLSMN1; SMN2ALDH1A1 | |
| SCHEMBL11727844 | 0.70 | ALDH1A1 (0.54) | CES2CES1SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300688-A1 | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them | FISONS plc (GB) | 1989-01-25 | — | — | EP | disclosed |