Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.71 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.71 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.71 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.71 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.71 |
| ▸ | DHFR | P00374 | 1/20 | 0.71 |
| ▸ | MPO | P05164 | 1/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.71 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.71 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.71 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.71 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262003 | 0.86 | PTGS2 (0.69) | PTGS2LMNAPTGS1MEN1CYP1A2 | |
| SCHEMBL10518206 | 0.84 | MT-CO2 (0.73) | PTGS2LMNAPTGS1MEN1CYP1A2 | |
| SCHEMBL10513885 | 0.84 | PTGS2 (0.51) | PTGS2LMNAPTGS1MEN1CYP1A2 | |
| SCHEMBL7925344 | 0.83 | PTGS2 (0.76) | PTGS2LMNAPTGS1MEN1CYP1A2 | |
| Mefenamic Acid SCHEMBL29350572 | 0.83 | PTGS2 (1.00) | PTGS2LMNAPTGS1MEN1CYP1A2 | |
| Mefenamic Acid SCHEMBL3544 | 0.83 | PTGS2 (1.00) | PTGS2LMNAPTGS1MEN1CYP1A2 | |
| Mefenamic Acid SCHEMBL29355128 | 0.83 | PTGS2 (1.00) | PTGS2LMNAPTGS1MEN1CYP1A2 | |
| Mefenamic Acid SCHEMBL6421234 | 0.83 | PTGS2 (1.00) | PTGS2LMNAPTGS1MEN1CYP1A2 | |
| Mefenamic Acid SCHEMBL29465887 | 0.83 | PTGS2 (1.00) | PTGS2LMNAPTGS1MEN1CYP1A2 | |
| SCHEMBL24172126 | 0.83 | PTGS2 (0.70) | PTGS2LMNAPTGS1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155110-A | Antiinflammatory agents, analgesics, antipyretics | WARNER-LAMBERT COMPANY (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0316630-A1 | Novel fenamic acid hydroxamate derivatives having cyclooxygenase and 5-lipoxygenase inhibition | WARNER-LAMBERT COMPANY (US) | 1989-05-24 | — | — | EP | disclosed |
| WO-1989003818-A1 | NOVEL FENAMIC ACID HYDROXAMATE DERIVATIVES HAVING CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITION | WARNER-LAMBERT COMPANY (US) | 1989-05-05 | — | — | WO | disclosed |