Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.76 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.76 |
| ▸ | LMNA | P02545 | 3/20 | 0.76 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.76 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.76 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.76 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.76 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.76 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.76 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.76 |
| ▸ | DHFR | P00374 | 1/20 | 0.76 |
| ▸ | MPO | P05164 | 1/20 | 0.76 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.76 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321483 | 0.87 | AKR1C3 (0.57) | PTGS2AKR1C3LMNAAKR1C2MEN1 | |
| Mefenamic Acid SCHEMBL29355128 | 0.86 | PTGS2 (1.00) | PTGS2AKR1C3LMNAAKR1C2MEN1 | |
| Mefenamic Acid SCHEMBL6421234 | 0.86 | PTGS2 (1.00) | PTGS2AKR1C3LMNAAKR1C2MEN1 | |
| Mefenamic Acid SCHEMBL3544 | 0.86 | PTGS2 (1.00) | PTGS2AKR1C3LMNAAKR1C2MEN1 | |
| Mefenamic Acid SCHEMBL29350572 | 0.86 | PTGS2 (1.00) | PTGS2AKR1C3LMNAAKR1C2MEN1 | |
| Mefenamic Acid SCHEMBL29465887 | 0.86 | PTGS2 (1.00) | PTGS2AKR1C3LMNAAKR1C2MEN1 | |
| SCHEMBL25449209 | 0.85 | AKR1C3 (0.66) | PTGS2AKR1C3LMNAAKR1C2MEN1 | |
| SCHEMBL11013710 | 0.85 | PTGS2 (0.73) | PTGS2AKR1C3LMNAAKR1C2MEN1 | |
| Mefenamic Acid SCHEMBL16179956 | 0.85 | PTGS2 (0.97) | PTGS2AKR1C3LMNAAKR1C2MEN1 | |
| Mefenamic Acid SCHEMBL678182 | 0.85 | PTGS2 (0.97) | PTGS2AKR1C3LMNAAKR1C2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4272761-A2 | COMPOSITIONS FOR TREATING OPHTHALMIC CONDITIONS | Medicon Pharmaceuticals, Inc. (US) | 2023-11-08 | — | — | EP | disclosed |
| US-20230293557-A1 | COMPOSITIONS AND METHODS FOR TREATING OPHTHALMIC CONDITIONS | MEDICON PHARMACEUTICALS INC (US) | 2023-09-21 | — | — | US | disclosed |
| US-20230293557-A1 | COMPOSITIONS AND METHODS FOR TREATING OPHTHALMIC CONDITIONS | MEDICON PHARMACEUTICALS INC (US) | 2023-09-21 | — | — | US | disclosed |
| US-20230219886-A1 | NOVEL SELENO-NSAID ANALOGS AND USES THEREOF | THE PENN STATE RESEARCH FOUNDATION | 2023-07-13 | — | — | US | disclosed |
| WO-2018115984-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION | CELLIX BIO PRIVATE LIMITED (IN) | 2018-06-28 | — | — | WO | disclosed |
| WO-2018064354-A1 | COMPOSITIONS AND METHODS FOR TREATING OPHTHALMIC CONDITIONS | MEDICON PHARMACEUTICALS, INC. (US) | 2018-04-05 | — | — | WO | disclosed |
| US-20150306232-A1 | HYDROGELATORS COMPRISING D-AMINO ACIDS | BRANDEIS UNIVERSITY | 2015-10-29 | — | — | US | disclosed |
| US-20150148306-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION | KANDULA MAHESH (IN) | 2015-05-28 | — | — | US | disclosed |
| WO-2014091467-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF AUTOIMMUNE DISEASES AND INFLAMMATION | KANDULA MAHESH (IN) | 2014-06-19 | — | — | WO | disclosed |
| WO-2014083476-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC AND LIPID DISORDERS | KANDULA MAHESH (IN) | 2014-06-05 | — | — | WO | disclosed |
| US-8569335-B2 | Compounds derived from taurine, process of their preparation and pharmaceutical compositions containing these | EMS S.A. (BR) | 2013-10-29 | — | — | US | disclosed |
| US-20110118303-A1 | NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE | EMS S.A. (BR) | 2011-05-19 | — | — | US | disclosed |
| US-20110118303-A1 | NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE | EMS S.A. (BR) | 2011-05-19 | — | — | US | disclosed |
| WO-2009124371-A9 | NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE | EMS S. A. (BR) | 2010-12-02 | — | — | WO | disclosed |
| US-20100298360-A1 | SMALL MOLECULE INHIBITORS OF PDZ INTERACTIONS | BELMARES MICHAEL P | 2010-11-25 | — | — | US | disclosed |
| WO-2010078486-A2 | OPIOID-CONTAINING ORAL PHARMACEUTICAL COMPOSITIONS AND METHODS | UPSHER-SMITH LABORATORIES, INC. (US) | 2010-07-08 | — | — | WO | disclosed |
| WO-2009124371-A2 | NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE | EMS S. A. (BR) | 2009-10-15 | — | — | WO | disclosed |
| US-20090062213-A1 | Small Molecule Inhibitors of PDZ Interactions | ARBOR VITA CORPORATION (US) | 2009-03-05 | — | — | US | disclosed |
| US-7432261-B2 | Anti-inflammatory phosphonate compounds | GILEAD SCIENCES, INC. (US) | 2008-10-07 | — | — | US | disclosed |
| US-20080227684-A1 | Small Molecule Inhibitors of PDZ Interactions | NONO INC. (CA) | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062213-A1 | Small Molecule Inhibitors of PDZ Interactions | PDLIM5, DAB2IP, PSD | PTGS2 4529/4885AKR1C3 4659/4885LMNA 4338/4885 |
| US-20150148306-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION | IAPP, TTR, GPR119 | PTGS2 2226/4885AKR1C3 400/4885LMNA 2155/4885 |
| US-20230293557-A1 | COMPOSITIONS AND METHODS FOR TREATING OPHTHALMIC CONDITIONS | PDE6C, PDE6H, PDE6D | PTGS2 101/4885AKR1C3 191/4885LMNA 816/4885 |
| US-20150306232-A1 | HYDROGELATORS COMPRISING D-AMINO ACIDS | DNPEP, S100A10, S100A11 | PTGS2 622/4885AKR1C3 4569/4885LMNA 4707/4885 |
| US-20080227684-A1 | Small Molecule Inhibitors of PDZ Interactions | PDLIM5, DAB2IP, PSD | PTGS2 4529/4885AKR1C3 4659/4885LMNA 4338/4885 |
| US-20100298360-A1 | SMALL MOLECULE INHIBITORS OF PDZ INTERACTIONS | PDLIM5, DAB2IP, PSD | PTGS2 4529/4885AKR1C3 4659/4885LMNA 4338/4885 |
| US-20110118303-A1 | NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE | TPMT, UTS2R, NSUN3 | PTGS2 217/4885AKR1C3 594/4885LMNA 3909/4885 |
| US-20230219886-A1 | NOVEL SELENO-NSAID ANALOGS AND USES THEREOF | SELENOI, SCLY, GPX1 | PTGS2 14/4885AKR1C3 1586/4885LMNA 4147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.