Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TTK | P33981 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1177434 | 0.78 | HTR6 (0.45) | ALDH1A1HSD17B10HTR6 | |
| SCHEMBL5784803 | 0.74 | MAPT (0.78) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL5261284 | 0.72 | ALDH1A1 (0.49) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9737712 | 0.72 | ALDH1A1 (0.49) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9737778 | 0.72 | MAPT (0.60) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL19717983 | 0.71 | ALDH1A1 (0.52) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL11015974 | 0.70 | CA2 (0.47) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL6567341 | 0.70 | EGFR (0.50) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL3114538 | 0.70 | ALDH1A1 (0.55) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7245923 | 0.69 | CA2 (0.65) | MAPTALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079363-A | From an alkoxypyridine and an indole derivative, antitumor and antileukemia agents | SANOFI (FR) | 1992-01-07 | — | — | US | disclosed |