Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734747 | 0.85 | NSD2 (0.32) | NSD2ABL1PPARGRIN1L3MBTL1 | |
| SCHEMBL9735525 | 0.80 | KDM4E (0.33) | ABCB1MALT1 | |
| SCHEMBL9737646 | 0.79 | SCN8A (0.33) | ABCB1MALT1SCN8ASCN10AMAOB | |
| SCHEMBL9736303 | 0.79 | MALT1 (0.36) | ABCB1MALT1MAOBPDE4APDE4B | |
| SCHEMBL9732950 | 0.78 | PDPK1 (0.33) | ABCB1MALT1SCN8ASCN10AMAOB | |
| SCHEMBL9371852 | 0.76 | SCN8A (0.33) | ABCB1MALT1SCN8ASCN10AMAOB | |
| SCHEMBL8130227 | 0.75 | SCN8A (0.35) | SCN8ASCN10ANSD2ABL1PPARG | |
| SCHEMBL9735328 | 0.71 | MAOB (0.33) | ABCB1MALT1MAOBPDE4APDE4B | |
| SCHEMBL9200740 | 0.70 | ABCC9 (0.41) | ABCB1 | |
| SCHEMBL9735762 | 0.69 | ABCC9 (0.42) | ABCB1MALT1MAOBPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |