Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735400 | 0.86 | KDM4E (0.35) | KDM4ELMNANPC1RAB9AALDH1A1 | |
| SCHEMBL9736173 | 0.80 | LMNA (0.32) | KDM4ELMNANPC1RAB9AALDH1A1 | |
| SCHEMBL9737151 | 0.80 | ABCB1 (0.32) | ABCB1MALT1 | |
| SCHEMBL9733219 | 0.79 | LMNA (0.32) | KDM4ELMNANPC1RAB9AALDH1A1 | |
| SCHEMBL9372031 | 0.78 | KDM4E (0.33) | KDM4ELMNANPC1RAB9AALDH1A1 | |
| SCHEMBL9736303 | 0.78 | MALT1 (0.36) | LMNAABCB1MALT1 | |
| SCHEMBL8090676 | 0.75 | PDE4A (0.35) | KDM4ELMNANPC1RAB9AALDH1A1 | |
| SCHEMBL9735328 | 0.70 | MAOB (0.33) | ABCB1MALT1 | |
| SCHEMBL9735910 | 0.70 | ABCC9 (0.42) | KDM4ELMNAABCB1 | |
| SCHEMBL9737765 | 0.69 | ABCB1 (0.38) | KDM4EABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |