Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738641 | 0.85 | NSD2 (0.33) | CYP3A4NSD2ABL1PPARGRIN1 | |
| SCHEMBL9737886 | 0.83 | TLK2 (0.32) | NSD2ABL1PPARGRIN1L3MBTL1 | |
| SCHEMBL9732950 | 0.83 | PDPK1 (0.33) | SCN8ASCN10AMAOBABCB1MALT1 | |
| SCHEMBL9739750 | 0.82 | BRD4 (0.35) | CYP3A4NSD2ABL1PPARGRIN1 | |
| SCHEMBL9737102 | 0.82 | CNR2 (0.37) | PDPK1 | |
| SCHEMBL9733219 | 0.80 | LMNA (0.32) | CYP3A4ALOX15ABCC9ABCB1MALT1 | |
| SCHEMBL9737151 | 0.79 | ABCB1 (0.32) | SCN8ASCN10AMAOBABCB1NSD2 | |
| SCHEMBL8130227 | 0.78 | SCN8A (0.35) | SCN8ASCN10ANSD2ABL1PPARG | |
| SCHEMBL9737221 | 0.77 | MALT1 (0.35) | CYP3A4ALOX15MAOBABCC9ABCB1 | |
| SCHEMBL9371852 | 0.76 | SCN8A (0.33) | SCN8ASCN10AMAOBABCC9ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143924-A | OXODIHYDROPYRIDYL CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |