Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | APC | P25054 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737322 | 1.00 | CTSK (0.39) | CTSKCYP1A2PNMTACEMME | |
| SCHEMBL2549268 | 0.91 | PNMT (0.43) | PNMTACENPC1RAB9AEPHX1 | |
| SCHEMBL2549264 | 0.91 | PNMT (0.43) | PNMTACENPC1RAB9AEPHX1 | |
| SCHEMBL31026357 | 0.90 | SDCBP (0.43) | CTSKCYP1A2PNMTMMENPC1 | |
| SCHEMBL29084932 | 0.90 | SDCBP (0.43) | CTSKCYP1A2PNMTMMENPC1 | |
| SCHEMBL5689687 | 0.88 | PNMT (0.44) | CTSKCYP1A2PNMTMMENPC1 | |
| SCHEMBL30762790 | 0.88 | PNMT (0.44) | CTSKCYP1A2PNMTMMENPC1 | |
| SCHEMBL22804044 | 0.88 | PNMT (0.44) | CTSKCYP1A2PNMTMMENPC1 | |
| SCHEMBL8303924 | 0.88 | PNMT (0.44) | CTSKCYP1A2PNMTMMENPC1 | |
| SCHEMBL21633435 | 0.87 | ACE (0.48) | PNMTACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130307-A | Antibody inhibitors; treating organ graft rejection, fungal infections; antiinflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-07-14 | — | — | US | disclosed |