Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NOD2 | Q9HC29 | 4/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10555991 | 0.90 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTNOD2NOD1 | |
| SCHEMBL10555109 | 0.86 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPTNOD2NOD1 | |
| SCHEMBL10553281 | 0.84 | LMNA (0.47) | ALDH1A1LMNAMAPTNOD2NOD1 | |
| SCHEMBL10003056 | 0.83 | NOD2 (0.65) | ALDH1A1LMNAMAPTNOD2NOD1 | |
| SCHEMBL27139067 | 0.82 | NOD2 (0.52) | ALDH1A1LMNAMAPTNOD2NOD1 | |
| SCHEMBL10002935 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTNOD2NOD1 | |
| SCHEMBL15882629 | 0.81 | NOD1 (0.50) | ALDH1A1LMNAMAPTNOD2NOD1 | |
| SCHEMBL27139621 | 0.80 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTNOD2NOD1 | |
| SCHEMBL27139625 | 0.80 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTNOD2NOD1 | |
| SCHEMBL10553874 | 0.80 | RECQL (0.52) | ALDH1A1LMNAMAPTNOD1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260062443-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMA INC (US) | 2026-03-05 | — | — | US | disclosed |
| WO-2024044098-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-29 | — | — | WO | disclosed |
| US-5079363-A | From an alkoxypyridine and an indole derivative, antitumor and antileukemia agents | SANOFI (FR) | 1992-01-07 | — | — | US | disclosed |
| US-4831144-A | 1H-pyrrolo [3,2-c]pyrrolidines protected in 1-position useful as intermediates | SANOFI (FR) | 1989-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062443-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | C9, SSB, C1S | ALDH1A1 3835/4885LMNA 345/4885MAPT 1355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.