Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 5/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737252 | 0.80 | TLR8 (0.35) | TLR8HPGDCRACR2AGAAMAPT | |
| SCHEMBL9737369 | 0.79 | MAPK14 (0.40) | TLR8HPGDCRACR2ARAF1GAA | |
| SCHEMBL9737374 | 0.78 | KDM4E (0.46) | TLR8POLBHPGDMAPTNPSR1 | |
| SCHEMBL9739162 | 0.76 | MAPK14 (0.38) | TLR8CRACR2AHCRTR1HCRTR2 | |
| SCHEMBL9739960 | 0.69 | HSP90AA1 (0.39) | HPGDMAPTLMNAMEN1HTT | |
| SCHEMBL9737393 | 0.69 | ALDH1A1 (0.43) | HPGDMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9738838 | 0.68 | HSP90AA1 (0.38) | POLBHPGDCYP1A2GAAMAPT | |
| SCHEMBL9737486 | 0.67 | HSP90AA1 (0.37) | POLBHPGDCYP1A2GAAMAPT | |
| SCHEMBL9739285 | 0.67 | CYP3A4 (0.39) | CYP2D6LMNAMEN1KMT2A | |
| SCHEMBL9739031 | 0.66 | KMT2A (0.39) | POLBHPGDCYP1A2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5159078-A | Herbicides, plant growth regulator | CIBA-GEIGY CORPORATION (US) | 1992-10-27 | — | — | US | disclosed |
| US-4966622-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1990-10-30 | — | — | US | disclosed |