Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | CRACR2A | Q9BSW2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739162 | 0.94 | MAPK14 (0.38) | MAPK14TLR8TRPV1CRACR2A | |
| SCHEMBL9737076 | 0.81 | MAPK14 (0.43) | MAPK14MAPTALDH1A1GAAHPGD | |
| SCHEMBL9737730 | 0.79 | TLR8 (0.35) | TLR8MAPTKDM4EALDH1A1GAA | |
| SCHEMBL9738335 | 0.79 | MAPK14 (0.39) | MAPK14MAPTALDH1A1GAAHPGD | |
| SCHEMBL9737252 | 0.77 | TLR8 (0.35) | TLR8MAPTKDM4EALDH1A1GAA | |
| SCHEMBL9740354 | 0.76 | MAPK14 (0.39) | MAPK14MAPTALDH1A1HPGDLMNA | |
| SCHEMBL9738360 | 0.76 | MAPK14 (0.41) | MAPK14GAALMNA | |
| SCHEMBL9737104 | 0.76 | LMNA (0.40) | MAPK14MAPTALDH1A1HPGDLMNA | |
| SCHEMBL9737747 | 0.73 | PTGES (0.36) | MAPK14MAPTGAA | |
| SCHEMBL9739327 | 0.72 | SDHB (0.39) | MAPK14KDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5159078-A | Herbicides, plant growth regulator | CIBA-GEIGY CORPORATION (US) | 1992-10-27 | — | — | US | disclosed |
| US-4966622-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1990-10-30 | — | — | US | disclosed |